New study: Butyrate may strengthen the gut and reduce IBS symptoms
A newly published study from Örebro University brings promising news for anyone living with IBS. Researchers found that butyrate – a naturally occurring fatty acid produced when we eat dietary fiber – can make the gut more resilient and less sensitive.
What did the researchers do?
Butyrate is a naturally occurring fatty acid produced when we eat dietary fiber.
For the first time, researchers examined how butyrate affects the human colon directly. Usinga safe medical procedure, a small section of the colon was isolated, butyrate was added, and tissue samples were taken before and after exposure.
Both individuals with IBS and healthy controls participated.
The results were encouraging
The study showed that butyrate:
- reduced gut sensitivity
- decreased intestinal permeability (“leaky gut”) in IBS patients
- strengthened the gut barrier
- increased the colon’s resistance to stress
These findings open the door to new and potentially more effective future treatments.
What does this mean for you?
The results underline how important dietary fiber is for gut health, since fiber is what enables the body to naturally produce butyrate. A gut-friendly, fiber-rich diet can therefore:
- help calm IBS symptoms
- reduce gut hypersensitivity
- support a stronger and healthier gut barrier
- contribute to a more stable digestive system
This aligns well with today’s dietary recommendations for IBS and gives hope for improved future treatment options.


